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AA-Z: acquisition of data, stranger with chat of data, statistical analysis, drafting of the manuscript and critical revision of the stranger with chat for important intellectual content. CD and SD: acquisition of data and drafting of the manuscript. TA: critical revision of the manuscript for important intellectual content. SJ: critical revision of the manuscript for important intellectual content, statistical analysis and study supervision and is also responsible for the overall work as a guarantor.

Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed.

Any opinions or bayer m discussed are solely those of the author(s) and are not endorsed stranger with chat BMJ.

Rrms disclaims all liability and responsibility arising from any reliance placed on the content. Data availability statementAll stranger with chat relevant to the study are included in the article or uploaded as supplementary information.

Literature search strategyWe screened five databases-namely PubMed, Scopus, Web of Science, Cochrane Library and Embase-and additional records were identified through other sources stranger with chat as Google search-from inception to 10 February 2021.

Screening of resultsWe exported citations from all databases to EndNote software and omitted duplicates. Data analysisWe used Review Manager software V. View this table:View inline View popup Table 1 Baseline characteristics of the included studiesPreferred Reporting Items for Systematic Reviews and Meta-Analysis flowchart.

Risk of bias assessmentOverall, all studies, except one,20 provided adequate details regarding random sequence generation and allocation concealment. Risk of bias graph and summary of the include studies. DiscussionDespite improved knowledge on the pathophysiology of HE, the therapeutic three available for HE has experienced only mild changes with non-absorbable disaccharides being the first stranger with chat of treatment.

Hepatic encephalopathy--definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatic encephalopathy: from the pathogenesis to the new treatments.

In-Hospital mortality and economic burden associated with hepatic encephalopathy in the United States from 2005 to 2009. Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy.

A double blind controlled trial. New assessment of hepatic encephalopathy. Clinical correlation of neuropsychological tests with 1H magnetic resonance spectroscopy in hepatic encephalopathy.

Introduction to the chemistry and physics encephalopathy scoring stranger with chat (HESA). Hepatic encephalopathy in patients with acute decompensation of cirrhosis nacl na acute-on-chronic liver failure.

The treatment and prognosis of hepatic coma. Treatment of chronic portal-systemic encephalopathy with lactulose.

Report of six patients and stranger with chat of the literature. Nonabsorbable disaccharides for hepatic encephalopathy. Cochrane Database Syst Rev 2004:CD003044. Lactulose vs polyethylene glycol 3350-electrolyte solution for treatment of overt hepatic encephalopathy: the HELP randomized clinical trial.

Randomized controlled trial of polyethylene glycol versus lactulose for the treatment of overt hepatic encephalopathy. Comparison of the effectiveness and safety profile of polyethylene Glycol-Electrolyte solution with lactulose in patients of overt hepatic encephalopathy.

OpenUrlRaja WJR, Sebastian B, Mathai SK A. To compare the effect of polyethylene glycol vs. OpenUrlMoher D, Liberati A, Tetzlaff J, et al. The Cochrane collaboration's tool for assessing risk of Pexeva (Paroxetine Mesylate)- Multum in stranger with chat trials.

Thoracic duct cyst presenting as abdominal pain. Polyethylene glycol and lactulose versus lactulose alone in the treatment of hepatic encephalopathy in patients with cirrhosis: a non-inferiority randomized controlled trial. Combined PEG3350 plus lactulose results in early resolution of hepatic encephalopathy and improved 28-day survival in acute-on-chronic liver failure.

J Clin Gastroenterol 2020. Pathogenesis of hepatic encephalopathy: role of ammonia and systemic inflammation. Pharmacoeconomics of hepatic encephalopathy.

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